STILLWATER, Okla. -- On a night with serious national championship implications, No. 3 Oklahoma State showed what the Big 12's thrilling offenses bring to the table.

Brandon Weeden threw for a school-record 502 yards and four touchdowns, and Joseph Randle scored the final, tiebreaking 23-yard touchdown with 2:16 remaining to lift No. 3 Oklahoma State to a 52-45 victory against Kansas State (No. 14 BCS, No. 17 AP) on Saturday night.

While top-ranked LSU was edging out No. 2 Alabama 9-6 to get a leg up in the SEC's part of the BCS picture, Weeden and the Cowboys (9-0, 6-0 Big 12) won their own version of a wild one that came right down to the end.

"I'm sure that one was pretty fun as well," Weeden said. "To come out on top in this one feels really, really good."

The Cowboys matched the best start in school history -- accomplished only during the 1945 team's perfect Sugar Bowl season -- and survived quite a scare from K-State (7-2, 4-2), which had three shots at the end zone from the OSU 5 in the final 12 seconds.

Collin Klein missed on passes intended for Tyler Lockett and Chris Harper and then overshot Tramaine Thompson in the end zone as time expired. Oklahoma State's players rushed on to the field to celebrate, their national championship hopes still intact.

OKLAHOMA 41, TEXAS A&M 25
NORMAN, Okla. -- Oklahoma (No. 6 BCS, No. 7 AP) lost a lot in a victory over Texas A&M.

All-American Ryan Broyles, the NCAA's career leader in receptions, tore the anterior cruciate ligament in his left knee and will miss the remainder of the season.

He got hurt while cutting to make his second catch of the game, a 30-yarder that set up one of four third-quarter touchdowns in the Sooners' 41-25 victory Saturday.

"It's just a bad deal," quarterback Landry Jones said. "You hate for something like that to happen to such a good guy."

Broyles left the field in tears. He entered the game averaging 13.2 yards on 81 catches. His two catches went for 57 and 30 yards.

"He's such a special, special player," coach Bob Stoops said. "It's deflating for him and for all of us. ... Your heart drops when you first hear it."

The Sooners (8-1, 5-1 Big 12) scored on four straight possessions after leading 13-10 at halftime. Texas A&M (5-4, 3-3) had its second-half troubles continue -- the Aggies gave up big second-half leads in its previous three losses.